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Immunodiagnostics
The
MycoDot test employs liparabinomannan (LAM) antigen
bound to plastic combs. When the combs are incubated in
diluted serum, specific anti-LAM antibodies from the sample,
if present, bind to the antigen. The combs are then washed
to remove non-specific antibody, and incubated in a suspension
of colored particles which bind to the bound anti-LAM antibodies.
If enough of the specific antibodies are present in the
serum sample, a colored spot will form where the antigen
is attached to the plastic comb. The sensitivity of the
test is calibrated so that only cases of active mycobacterial
disease such as tuberculosis will provide a positive reaction
by MycoDot.
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Marketing Brochure
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